Membrane interactions of designed cationic antimicrobial peptides: The two thresholds
نویسندگان
چکیده
منابع مشابه
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Antimicrobial peptides are known to selectively disrupt (highly charged) microbial membranes by asymmetrical incorporation into the outer layers. We present a physical basis for membrane-charge selectivity of cationic antimicrobial peptides. In particular, we provide a clear picture of how peptide-charge Q influences the asymmetrical insertion--one salient feature is the existence of an optimal...
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ژورنال
عنوان ژورنال: Biopolymers
سال: 2008
ISSN: 0006-3525,1097-0282
DOI: 10.1002/bip.20917